Main Article Content
The cause of Crohn’s Disease (CH) and Ulcerative Colitis (UC) is infl ammatory bowel disease (IBD) in which the genetic and environmental factors play a role in the pathogenesis. The incidence of UC in the whole world has been reported as 6.3-24.3 / 100.000, and the incidence of CH 5-20.2 / 100.000 . In Turkey, the prevalence of IBD is 36 / 100.000 according to the data of 2007.
There are still signifi cant unmet needs in the treatment strategies for infl ammatory bowel disease, along with the growing developments in recent years. Patients are seeking safer, immunomodulatory and immunosuppressive treatment alternatives, and modulation of intestinal microbiota in IBD seems conceptually attractive and realistic . However, the inconsistent results in the studies and publications still do not provide suffi cient evidence on the subject and therefore studies are insuffi cient to assess the clinical fi ndings of the fi ndings obtained.
In this article, the etiopathogenetic and therapeutic relationship between IBD and intestinal microbiota has been tried to be observed in the light of current knowledge